For some people, getting pregnant right away is natural, whereas for others, it takes some time, depending on their health conditions. Having a baby is a fantastic experience. After marriage, most people wish to have a baby; it is a perk of happy moments for women.
Pregnancy is essential for healthy babies. You have to prepare your body for a baby delivery. Some of the factors involved in pregnancy are age, timing, frequency of intercourse, adequate nutrition supply to the body, healthy weight, length of time you are trying to conceive, duration of your marriage life, hormones, lifestyle patterns, and any other health issues.
Ovulation is essential: Ovulation is the process by which the mature egg (oocyte) is released from the ovary during the menstrual cycle. Preparing for pregnancy (helpful for fertilization) is the most important thing for women to do.
How ovulation occurs: When a woman releases a mature egg from the ovary, it moves down into the fallopian tubes and stays for 12 to 24 hours, where it can be fertilized. Male sperm can live inside the female reproductive tract after five days of sexual intercourse. At the time, pregnancy chances were high.
Therefore, the drug Clomid was introduced to treat ovulation problems in women; it is very effective at treating and stimulating ovulation. It is the most popular fertility drug widely prescribed.
Clomid is suitable for people who don’t ovulate independently and have irregular ovulation (PCOS) coupled with a low sperm count. Clomid’s success rate is essential. Let’s understand in detail.
What Is Clomid?
Clomid or clomiphene is a drug used to treat infertility in women. Women produce eggs every month. When women do not have adequate ovum (egg) production but wish to become pregnant, they may not be able to do so. Pregnancy will not take place; therefore, infertility takes place.
This medication is used for women who have infertility in women. It helps release the mature eggs in the ovary by stimulating hormones.
Another name for Clomid is Clomiphene citrate, which is used as an oral medication. Clomid medication is used after the age of 40. The medicine is ineffective for older people because it significantly reduces fertility potential.
How Does Clomid Work?
Clomid belongs to an ovulatory stimulant that acts as a selective estrogen receptor modulator. The drug works on the female hormone estrogen, which helps produce mature eggs in the ovaries.
Clomid is a drug that helps in a process called ovulation. After taking the medication, it will directly trigger or stimulate the pituitary gland located in the bra. It’s an important gland that helps to secrete the hormones called gonadotropins.
These hormones include FSH (follicle-stimulating hormones) and LH (luteinizing hormones). It works on the ovary in the female body by maturing the follicles and inducing ovulation (releasing eggs from the ovary).
It is advised to take Clomid for around six cycles only due to the increased risk of ovarian cancer if you use more than 12 cycles. You have to take the drug daily at the same time.
What is the Success rate of Clomid?
The success rate depicts all medicine’s positive and negative aspects. Most people look for it before knowing its effects. Clinical trials and the effectiveness of the medication on people would create the best success rate for a drug to work.
The clomid success rate was around 80% in ovulation. In terms of Clomid, It would mostly show its effects within three months.
A study was conducted on the two medicines (Clomid and Letrozole) to observe their impact on ovulation. J Saha et al. conducted the research.
The overall study was followed to evaluate the most effective drug for people who are not able to become pregnant. It was observed among 165 people who were suffering from infertility.
The overall study was divided into three groups. It was observed for 21 days following the menstrual cycle. The study showed that Clomid was highly successful in giving better results than Letrozole.
Things You Should Know About Clomid:
Track Record:
In 1967, Clomid’s first successful clinical trials were published. FDA approved it in 1967; all gynecologists and fertility specialists have trusted Clomid for 50 years, and it comes as a prescription for safe fertility medications.
First treatment in ovulation:
Clomid is a drug used in PCOS females who cannot produce eggs in their ovaries. It stimulates your hypothalamus and pituitary glands to produce gonadotropin-releasing hormones, stimulating follicle and luteinizing hormones. These hormones will help mature the egg follicles and increase ovulation chances.
In the first treatment, Clomid is very successful in stimulating ovulation. According to the pregnancy cycle, only 10% to 13% will get pregnant. The main important thing is that the drug Clomid is not effective if you have infertility factors unrelated to ovulation. These factors include blocked tubes, ovarian failure, pelvic lesions, certain male infertility factors, etc.
Testing and diagnosis of infertility should be conducted in both partners to determine the exact cause of infertility. In some cases, the gynecologist will recommend a fertility specialist if you don’t get pregnant after using Clomid in two or more cycles.
Repeat Cycles:
People should typically repeat the cycle of consuming Clomid for treatment. Your doctor will closely monitor your performance; after three to six cycles, your doctor may perform alternative methods or any progressive fertility treatments if the pregnancy won’t happen.
Used within men:
Clomid plays a significant role in female health by helping in a process called ovulation. Widely, this medication was prescribed only for females, but now clomid is also prescribed for males to increase their sperm count and increase the testosterone hormones in the male body.
Chance of twins or triplets:
This Clomid will induce the releasing of eggs from the ovary, so there is a chance of getting twins or triplets in a woman’s womb. However, experienced fertility specialists suggest the correct dosage to avoid any other risks for a safe pregnancy.
When does Clomid Work the best?
First Month efficacy:
In recent research studies, during the Clomid treatment cycle, the odds of conceiving rate are 5.6% to 20%. Clomid effectiveness varies and depends upon the cause of infertility. Always remember that a person with no fertility problem has more chances of getting pregnant in any given month.
For some people, it won’t be possible in one month, so don’t panic if you don’t get pregnant. You can take more than one cycle. People often conceive between 30 and 36, which is about a year.
Conflicts of getting pregnant:
A literature review published in human reproduction considered several studies on Clomid. The success rate of women using Clomid was over 5,000 included. The study says
- 29% of People gave birth
- 36% of People achieved pregnancy,
- 73% of People eventually ovulated on Clomid
Due to miscarriages, the birth rate is lower than the pregnancy rate. Clomid doesn’t seem to increase the risk of miscarriage. Moreover, you must understand that Clomid, other than unrelated ovulation issues, will not be treated with Clomid.
Another study from Scotland looked at the success rate of couples diagnosed with unexplained infertility. Those couples were assigned into groups: Expectant management, Treatment with Clomid, and treatment with unstimulated intrauterine insemination ( IUI).
The IUI group was the influential treatment group, with a 22% live birth rate. Treatment with the Clomid group was 14%, and the couples who received no treatment had a 17% birth rate.
Best days to take clomid for success?
Clomid pills are usually taken for five days in a row at the beginning of your menstrual cycle. It can start on day two or five of your menstrual cycle. Most doctors usually prescribe taking it on days (2nd to 7th) or Days (5 to 8 and 9). It depends on how you react to the medication. Your doctor recommends a dosage cycle for you. It doesn’t matter which protocol date you follow; when it comes to inducing ovulation success rate, you are likely to take Clomid on days 3rd to 7th. Your doctor will tell you which Clomid protocol date you should follow.
Perfect Dosage:
The doctor first recommended the 50 mg lowest dose. If you don’t ovulate on 50 mg, your doctor may try one more cycle at the exact 50 mg dosage or increase the dosage, which depends on the individual’s condition.
Regarding dosage, a study found that only
- 46% of Women will ovulate at 50mg.
- 21% of Women will ovulate at 100mg.
- 8% of women will ovulate at 150 mg.
After increasing the dosage, if you don’t get pregnant, then do not panic. In some cases, increasing the dosage will not increase the odds of getting pregnant, and a higher dose will lead to side effects of Clomid and a reduction in the fertility rate.
When Clomid Doesn’t Work?
About one in four women, the drug Clomid will not work due to its dosage or any other unrelated ovulation factors.
related post: Can you drink alcohol while taking clomid
To whom it doesn’t work:
The clomid pill works only under the right circumstances and proper drug usage. People should understand it is not a magical fertility drug that causes pregnancy. It is unsuccessful in people with irregular or absent ovulation or if any other male infertility factors are involved.
The Clomid success rate will be low, and it won’t work well for women with age-related infertility issues, low estrogen levels, or women with primary ovarian insufficiency. It also does not work in women with ovulation problems caused by thyroid issues.
Women with Obese:
The most important thing is that everyone should maintain a healthy weight. In pregnancy, being overweight or underweight can reduce the chances of getting pregnant. Women who are obese have a high rate of pregnancy if they reduce their weight. You should consult with the doctor about the treatment.
Benefits and What if Clomid Does Not Work?
It is a cost-effective treatment for infertility compared to other treatments like IVF.
Clomid is an oral medication that is less invasive compared to other treatments.
Due to some possible reasons, Clomid cannot work. After taking the Clomid pill, you don’t get ovulation. These are some other things your doctor can try before suggesting different ways.
Other Factors to Improve Clomid Success:
After completing three cycles of Clomid, if the women do not become pregnant or are encouraged to have further testing before continuing the treatment.
The couple would like to continue with Clomid if all the test reports are regular. Other interventions might be noted, such as weight loss and weight gain.
Weight Loss:
Women who are overweight or obese may ovulate infrequently. They should perform a weight loss to achieve pregnancy. Overweight is defined as a BMI of more than 25 kg/m². Several ways to lose weight to gain a healthy and balanced weight are introduced. During the process, it has shown results in weight loss, and having an average weight will help in treatment with the help of Clomid.
Weight gain:
Women underweight and with BMI results of less than 17 kg/m² have eating disorders such as bulimia or anorexia, or those who exercise more robust regimens may ovulate irregularly or not at all.
These women are advised to gain weight and achieve the goal of a BMI of at least 19 kg/m², increase their calorie intake, and reduce high levels of strenuous exercise activity.
Metformin:
Metformin is a drug that is used in the treatment of type 2 diabetes mellitus. It is also used in women with PCOS and infertility cases of the drug Clomid treatment, and weight loss is not successful.
Metformin can also increase the chance of ovulation in women who did not produce ovulation on the drug Clomid alone; compared to Clomid treatment, it may not improve pregnancy rates. Hence, adding Clomid and Metformin is not recommended for women with PCOS unless they have pre-diabetes or type 2 diabetes. When the Clomid is unsuccessful, women should be attentive to the association between PCOS and insulin resistance.
Letrozole:
Letrozole is a medication used to treat women with breast cancer; it also works in ovulation induction for women with PCOS. The research found in 2014 that the use of Letrozole ovulation resulted in higher live birth rights. Letrozole has not yet been approved by the US Food Drug Administration (FDA) for ovulation induction.
Before consuming Clomid, What should you check?
Before consuming Clomid, you should have done some tests to ensure you took it for the right reason. Do a sperm count test for your partner because it would not help if your partner has a low sperm count. Before consuming Clomid, the person should be aware that she is not pregnant and has no ovarian cyst except polycystic ovary syndrome, abnormal uterine bleeding, fibroids, and abnormal liver function.
Some tests that need to be taken before consuming Clomid are pregnancy tests, estrogen levels, sperm count, prolactin levels, liver function tests, endometrial biopsy, and CD 3 FSH levels.
Success Rates of Clomid for PCOS and ovulation:
About three-fourths of women with PCOS are not ovulating. The drug Clomid will help you to ovulate at some dosing level. Women under 35 with PCOS have a 15% chance of getting pregnant. ( for 3 to 4 months) if they ovulate properly with Clomid.
The success rate of Clomid for getting pregnant with PCOS:
Studies say about 50% of women with the drug Clomid will get pregnant. It depends upon the women’s age and other factors. In some cases, in vitro fertilization may improve pregnancy chances for women under 35.
The success rate of IVF is about 70% for pregnancies with one IVF cycle and about 60% for live births. Always remember that Clomid will work only for your ovulation, not your pregnancy, unless you have difficulty getting pregnant and have issues with the quality of eggs, healthy sperm, open fallopian tube, and optimal weight.
Final Words From Druggist
By now, you must have known about the drug Clomid. As the drug is used to treat infertility in women, it helps to release the mature eggs in women’s ovaries, stimulating ovulation.
Clomid was a widely used fertility drug; about 80% of users showed a success rate in ovulation. It is advised to take only six cycles of Clomid. More than six cycles are not recommended due to serious side effects. You can get the medicine Over the counter. But for your benefit, you should talk to a doctor for your Safety.
How to make Clomid more successful?
Clomid is more effective if you lose weight before trying Clomid, and the best day to start is during day two of your menstrual cycle, or you can take it on Day five. Your doctor recommends the perfect day and dosage according to your body.
Do babies are born fit and healthy by consuming Clomid?
Clomid does not increase miscarriage; it helps stimulate ovulation, not the pregnancy rate. Taking Clomid may result in twins or triplets; in some cases, the baby is unhealthy.
After how many days does Clomid help you to ovulate?
Every medication works for a specific time, whereas in terms of Clomid, it usually takes over 5 to 12 days after the last Clomid tablet use.
How many eggs are produced during Clomid?
The average female body has copious amounts of follicles in the ovary. Still, in one cycle, only one egg will mature and be released from the ovary into a fallopian tube structure, where fertilization occurs.
But if they take Clomid, this will induce your hormone levels and allow your ovary to mature two or three eggs in just one month or cycle. So, there will be a high chance of pregnancy due to this action.